Food as Medicine: Boosting GLP-1 for Gut and Metabolic Harmony
By
Jasmine Reblando
What if there were foods that act as a natural form of Ozempic? A deep dive into fuel that promotes.
The gut-brain axis results in dynamic interactions of our mind and body’s cognition, mood, hunger and metabolism. A key player in this system is glucagon-like peptide-1 (GLP-1), a hormone secreted by intestinal L-cells in response to nutrient intake. GLP-1 regulates blood sugar, insulin secretion, and satiety while also playing roles in neuroprotection and mood stabilization.
In recent times, GLP-1 receptor agonists such as Ozempic, have revolutionized the way we manage metabolic disorders like type 2 diabetes and obesity. These powerful medications work by enhancing insulin secretion and reducing glucagon release, keeping blood sugar levels steady and under control. Some may even look to Ozempic to shed a few extra pounds here although it is not prescribed solely as a weight-loss alternative as they slow down gastric emptying and increase feelings of fullness, making it easier to eat less. On top of that, they’ve been shown to support heart health, lowering the risk of cardiovascular complications in people with diabetes.
But as incredible as these therapies are, they’re not without their drawbacks. Common side effects like nausea, the high cost of treatment, and the need for injectable delivery can make them less accessible or desirable for some. That’s where natural methods come in. What if we had a readily accessible ozempic alternative found right in our kitchens? By focusing on dietary and lifestyle strategies to naturally boost GLP-1 production, you can enjoy many of the same benefits while supporting your gut health and gut-brain axis.
What if we had a readily accessible ozempic alternative found right in our kitchens? Research has found that as ozempic is a GLP-1 hormone, many foods can promote the same results of combating type 2 diabetes and obesity.
Nature offers promising alternatives to synthetic GLP-1 agonists. Research is finding that natural compounds have shown the potential to stimulate GLP-1 secretion and regulate blood glucose effectively.
- Gingerol, a compound found in ginger, supports increased GLP-1 secretion and further promotes glucose tolerance, from a study done in mice with type 2 diabetes.
- Resveratrol, a compound found in blueberries, raspberries and red wine grapes, found to normalize blood glucose by increasing proglucagon mRNA expression and improving GLP-1 secretion in mouse models with diabetes.
- Glyceollins, a compound found in fermented soybeans as found in the popular Japanese dish, natto, have been found to increase secretion of GLP-1 in gut cells. By doing so, the potentiation of beta cell survival. Beta cells work to secrete insulin and inevitably lower the effects of sugar in the blood.
Harnessing natural compounds to modulate GLP-1 secretion offers an exciting therapeutic strategy for diabetes management. With fewer side effects and additional health benefits, herbal-based GLP-1 agonists could complement or even replace synthetic options. By embracing the power of plants, we may unlock new pathways to healthier lives.